Tip! Use this direct link for the [Anatomy & Physiology Research Guide](https://library.nwacc.edu/anatomy/home) and skip to step 5.

Navigate to [https://library.nwacc.edu/home/](https://library.nwacc.edu/home/)

Start with ar recommended ebook. Scroll select. Click to connect.

In this example, we are searching [*Mosby's*](https://discovery.ebsco.com/linkprocessor/plink?id=84cc85c4-df28-3548-8733-fffefd7eb97b) for the drug "Ozempic" -  You will be asked to logon to open the ebook.

Click the "Enter keyword, phrase, etc." field.

Type in the name of your drug. In this example, we are using "ozempic [[enter]]"

...Dose based on BSA RARELY USED semaglutide (Rx) Ozempic Func. class.: Antidiabetic USES: For the...

Alert! Not all results will take you to the correct entry. You may need to play around with this. This book is organized alphabetically by the generic drug name, if that helps.

Click here to generate a sample citation.

Click "APA 7th Edition (American Psychological Assoc.)"

APA 7th Edition (American Psychological Assoc.)

Go back to [the research guide](https://library.nwacc.edu/anatomy/drugs) to select a .gov site to search.

This is the librarian's favorite, but you can pick any! Click "[MedlinePlus Drugs](https://medlineplus.gov/druginformation.html)"

In this example, we will use the drug "ozempic" - Type "ozempic [[enter]]"

The generic name for "ozempic" is "semaglutide" - Click "Semaglutide Injection"

Go back to [the research guide](https://library.nwacc.edu/anatomy/drugs) to select an open access drug manual to search.

Select any you'd like, but we are using the librarian's favorite: [PDR](http://www.pdr.net/browse-by-drug-name)

Click "PDR: Prescribers' Digital Reference"

Click the "Type Drug Name Here" field. In this example, we type "ozempic [[enter]]"

Click open any area such as "Mechanism Of Action"

Go back to [the research guide](https://library.nwacc.edu/anatomy/drugs) to select a chemical database. Pick any you'd like, but we're using the librarian's favorite: [DrugBank](https://www.drugbank.ca/)

Type in the name of your drug. We are using "ozempic [[enter]]"

Find the date information you need for your citation here.

Summary

Semaglutide is a glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus.

Brand Names
Ozempic, Rybelsus, Wegovy
Generic Name
Semaglutide
DrugBank Accession Number
DB13928
Background

Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.1,15 Other members of this drug class include Exenatide and Liraglutide. Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection in December 2017.15 The tablet formulation was approved for oral administration in September 2019. Semaglutide works by binding to and activating the GLP-1 receptor, thereby stimulating insulin secretion and reducing blood glucose.14

The subcutaneous injection is administered once weekly and the tablet is administered once a day. Semaglutide offers a competitive advantage over other drugs used to manage diabetes, which may require several daily doses. Clinical trials have determined that this drug reduces glycosylated hemoglobin (HbA1c) levels and reduces body weight, proving to be effective for patients with type 2 diabetes.5 In June 2021, semaglutide was approved by the FDA for chronic weight management in adults with general obesity or overweight who have at least one weight-related condition, marking semaglutide as the first approved drug for such use since 2014.19 The use of semaglutide in weight management is also approved by Health Canada 20 and the EMA.21

On May 31, 2023, the FDA issued a warning regarding the use of compounded semaglutide after receiving adverse event reports. The use of salt forms of semaglutide, including semaglutide sodium and semaglutide acetate, has not been proven to be safe or effective.23

Type
Small Molecule
Groups
Approved, Investigational
Structure
Download
Similar Structures
Weight
Average: 4113.641
Monoisotopic: 4111.11537713
Chemical Formula
C187H291N45O59
Synonyms
Semaglutide
Sémaglutide
External ID

Go back to [the research guide](https://library.nwacc.edu/anatomy/drugs) to search for academic journal articles. Pick any you'd like, but we're using the librarian's favorite: [PubMed](https://library.nwacc.edu/pubmed)

Type your search terms. In this example we are searching: "ozempic and pharmacology [[enter]]"

Click "5 years" for the most recent research articles

Need more help? From the [research guide](https://library.nwacc.edu/anatomy/drugs), click "Ask Us!" to chat live with a librarian.

Click "Chat Now" during open hours, or ask a question when the library is closed

[Make an appointment with a librarian](https://nwacc.libwizard.com/f/bookalibrarian) we can help!

How to Find Drug Information Using NWACC Library Resources